Anti-HIV agents. New evidence changes guidelines about when to start treatment.

In the past year, HIV treatment guidelines from high-income countries and regions such as the United States, United Kingdom and Western Europe have changed. Generally, these guidelines now recommend that HIV positive people begin HAART when their CD4+ count has fallen below 350. This is a major shift from the beginning of this century, when treatment was usually delayed until CD4+ counts fell below the 200-cell mark.